Stem-cell replication to treat blood diseases

Use of Embryonic Stem Cells to Treat Severe Eye Diseases.

BACKGROUND The use of stem cells in regenerative medicine has major therapeutic potential. Recent clinical trials using cells derived from human stem cells are showing encouraging results, although these should be assessed with the necessary caution. DISCUSSION Some media have reported the results of these trials without due care, perhaps creating expectations that do not match the reality of...

Stem Cells to Treat Neurological Diseases - Implications for Neurosurgery

Stem cells: new opportunities to treat eye diseases.

The recent identification and characterization of neural progenitors with stem cell properties has opened new avenues that may be useful for treating functional impairments caused by the death of specific neural cell populations. Neuronal degeneration is the cause of debilitating visual impairment associated with prevalent ocular diseases, such as retinitis pigmentosa (RP), age-related macular ...

A hydrogel-based stem cell delivery system to treat retinal degenerative diseases.

Regenerative strategies for retinal degenerative diseases are limited by poor cellular survival, distribution and integration after transplantation to the sub-retinal space. To overcome this limitations a stem cell delivery system was developed, taking advantage of the minimally-invasive, injectable and biodegradable properties of a blend of hyaluronan and methylcellulose (HAMC). The physical a...

Advances in Hematopoietic Stem Cell Mobilization and Peripheral Blood Stem Cell Transplantation

Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...